Villarreal Clinic

  • Neuromodulators (Botox)
  • Sculptra (Biostimulator)
  • Hyaluronic Acid Fillers
  • Dr Gabriela Villarreal
    • EN
    • FR
    • IT
    • ES
    • DE
    • PL
  • Book an appointment
  • Neuromodulators (Botox)
  • Sculptra (Biostimulator)
  • Hyaluronic Acid Fillers
  • Dr Gabriela Villarreal
Book an appointment
EN FR IT ES DE PL

    Polynucleotides

    Polynucleotides: cellular regeneration and advanced skin revitalisation

    The most innovative aesthetic medicine treatments no longer seek only to correct visible signs of ageing, but to restore skin quality from its biological origin. Polynucleotides represent one of the most advanced therapies, acting directly on cellular regeneration and tissue repair mechanisms, offering authentic, progressive and deeply natural rejuvenation.

    What are polynucleotides and how do they work?

    Polynucleotides are highly purified DNA fragments, obtained through biotechnological processes, with an extraordinary capacity to stimulate cellular activity and promote tissue regeneration. Once infiltrated into the skin, they act at different levels:

    • Stimulate fibroblast proliferation
    • Favour collagen and elastin synthesis
    • Improve deep hydration
    • Protect against oxidative stress
    • Promote repair of cellular damage

    Indications

    Especially indicated for patients seeking to improve skin quality without altering volumes or facial features:

    • Global facial rejuvenation
    • Improvement of skin texture and radiance
    • Treatment of dehydrated or devitalised skin
    • Attenuation of fine lines
    • Improvement of mild sagging
    • Regeneration of delicate areas such as the eye contour
    • Rejuvenation of neck, décolleté and hands

    The procedure

    Superficial micro-injections in the areas to be treated, according to a personalised protocol. Duration: 20–30 minutes. Usually 2–4 sessions every 2–3 weeks. Outpatient procedure, with optional topical anaesthesia.

    Results

    • Initial improvement in hydration and radiance within a few days
    • Visible results from 2–3 weeks
    • Progressive improvement in skin quality in the following weeks
    • Cumulative results with each session

    Benefits

    • Deep stimulation of cellular regeneration
    • Improvement of skin quality, texture and elasticity
    • Increase in skin hydration
    • Natural rejuvenation without adding volume
    • Versatile treatment for face and other areas
    • Excellent tolerance and safety profile

    Safety and contraindications

    High safety profile. Mild and transient side effects: redness, small papules, mild bruising, slight sensitivity. Contraindicated during pregnancy, breastfeeding, active infections, uncontrolled autoimmune diseases, or hypersensitivity to components.

    Polynucleotides
Villarreal Clinic

Aesthetic Medicine

Navigation
  • Treatments
  • Doctors
  • Contact
Our Clinics
  • Sant Pere de Ribes
© 2026 Villarreal Clinic
Privacy Policy Legal Notice