Villarreal Clinic — Aesthetic Medicine in Sitges

Neuromodulators: the elegance of natural and precise rejuvenation

In the field of advanced aesthetic medicine, neuromodulator treatments have established themselves as one of the most sophisticated tools for preserving facial youth without resorting to invasive procedures. With a subtle and highly personalised approach, this treatment smooths expression lines, improves facial harmony and prevents premature ageing, always respecting the naturalness of expression.

What is a neuromodulator and how does it work?

Neuromodulators are substances derived from botulinum toxin that act selectively on the communication between nerve and muscle. Their function is to temporarily relax the muscular activity responsible for the formation of dynamic wrinkles — those that appear with repeated facial movement.

By reducing muscle contraction, the skin smooths progressively, resulting in a more rested, radiant and rejuvenated appearance. Far from "paralysing" expression, a well-executed treatment preserves natural gestures, avoiding a rigid or artificial look.

Indications: beyond wrinkles

Neuromodulators cover a range of aesthetic and therapeutic objectives:

• Smoothing of forehead expression lines
• Correction of frown lines (glabellar lines)
• Reduction of crow's feet
• Subtle eyebrow tail lift
• Improvement of gummy smile
• Facial oval definition through muscle relaxation
• Treatment of bruxism (teeth grinding)
• Reduction of excessive sweating (hyperhidrosis)

The procedure: precision and speed

The treatment is performed through micro-infiltrations at strategic points on the face, designed individually according to each patient's anatomy and goals. Duration: approximately 15–20 minutes. No anaesthesia or recovery time required.

Results: progressive, subtle and harmonious

Effects are not immediate, which contributes to a natural evolution of the result:

• First changes noticeable between 48 and 72 hours
• Optimal effect reached between 7 and 10 days
• Average duration: 4 to 6 months

Treatment benefits

• Facial rejuvenation without surgery
• Natural and personalised results
• Prevention of skin ageing
• Fast, safe and minimally invasive procedure
• No interruption to social or working life

Safety and contraindications

Excellent safety profile when performed by qualified professionals. Possible mild and transient side effects: localised redness, small bruises, slight tension. Contraindicated during pregnancy, breastfeeding, in patients with neuromuscular diseases, or with known hypersensitivity to components.

Sculptra: deep regeneration and progressive rejuvenation

In contemporary aesthetic medicine, rejuvenation is no longer based solely on filling or tightening, but on stimulating the skin's natural capacity to regenerate. Collagen biostimulators such as Sculptra represent one of the most advanced and elegant solutions to progressively and lastingly restore facial firmness, skin quality and volume.

What is Sculptra and how does it work?

Sculptra is a biostimulator composed of poly-L-lactic acid, a biocompatible and resorbable substance that acts on the deep layers of the skin. Unlike treatments that provide immediate volume, its mechanism stimulates the natural production of collagen — the protein responsible for skin firmness, elasticity and structure.

After application, a gradual process of dermal regeneration begins, improving skin density from within and achieving a global, natural and sustained rejuvenation.

Indications

Sculptra is especially indicated for volume loss and sagging associated with ageing:

• Recovery of lost facial volume
• Improvement of sagging in face and neck
• Definition of facial oval
• Attenuation of deep folds (nasolabial)
• Improvement of skin quality, density and texture
• Global rejuvenation without altering features

The procedure

Deep-layer skin infiltrations following a carefully planned medical protocol. Session duration: 30–45 minutes. Generally 2–3 sessions, spaced several weeks apart. Outpatient procedure with immediate return to normal routine.

Results

One of Sculptra's distinctive features is the progressiveness of its results:

• Initial improvement in the weeks following treatment
• Visible results from 4–6 weeks
• Maximum effect at 2–3 months
• Prolonged duration: up to 18–24 months

Benefits

• Stimulates natural collagen production
• Improves skin firmness, elasticity and density
• Progressively restores facial volume
• Long-lasting and natural results
• Minimally invasive treatment

Safety and contraindications

Excellent safety profile with extensive clinical backing. Mild and transient side effects: redness, small bruises, temporary sensitivity, occasional small nodules if post-treatment recommendations are not followed. Contraindicated during pregnancy, breastfeeding, active infections, uncontrolled autoimmune diseases, or tendency to keloids.

Polynucleotides: cellular regeneration and advanced skin revitalisation

The most innovative aesthetic medicine treatments no longer seek only to correct visible signs of ageing, but to restore skin quality from its biological origin. Polynucleotides represent one of the most advanced therapies, acting directly on cellular regeneration and tissue repair mechanisms, offering authentic, progressive and deeply natural rejuvenation.

What are polynucleotides and how do they work?

Polynucleotides are highly purified DNA fragments, obtained through biotechnological processes, with an extraordinary capacity to stimulate cellular activity and promote tissue regeneration. Once infiltrated into the skin, they act at different levels:

• Stimulate fibroblast proliferation
• Favour collagen and elastin synthesis
• Improve deep hydration
• Protect against oxidative stress
• Promote repair of cellular damage

Indications

Especially indicated for patients seeking to improve skin quality without altering volumes or facial features:

• Global facial rejuvenation
• Improvement of skin texture and radiance
• Treatment of dehydrated or devitalised skin
• Attenuation of fine lines
• Improvement of mild sagging
• Regeneration of delicate areas such as the eye contour
• Rejuvenation of neck, décolleté and hands

The procedure

Superficial micro-injections in the areas to be treated, according to a personalised protocol. Duration: 20–30 minutes. Usually 2–4 sessions every 2–3 weeks. Outpatient procedure, with optional topical anaesthesia.

Results

• Initial improvement in hydration and radiance within a few days
• Visible results from 2–3 weeks
• Progressive improvement in skin quality in the following weeks
• Cumulative results with each session

Benefits

• Deep stimulation of cellular regeneration
• Improvement of skin quality, texture and elasticity
• Increase in skin hydration
• Natural rejuvenation without adding volume
• Versatile treatment for face and other areas
• Excellent tolerance and safety profile

Safety and contraindications

High safety profile. Mild and transient side effects: redness, small papules, mild bruising, slight sensitivity. Contraindicated during pregnancy, breastfeeding, active infections, uncontrolled autoimmune diseases, or hypersensitivity to components.

Hyaluronic acid fillers: harmony, volume and natural rejuvenation

In aesthetic medicine, the art of rejuvenation lies in restoring the balance and harmony of the face while respecting its essence. Hyaluronic acid fillers are one of the most versatile and sophisticated tools to achieve this, allowing volumes to be recovered, wrinkles smoothed and contours redefined with natural and personalised results.

What is hyaluronic acid and how does it work?

Hyaluronic acid is a substance naturally present in our body, whose main function is to retain water and maintain hydration, elasticity and firmness of the skin. Over time, its concentration decreases, leading to loss of volume, sagging and the appearance of wrinkles.

Through infiltration at strategic points, hyaluronic acid restores lost volumes, deeply hydrates the skin, improves facial structure and support, and smooths wrinkles and folds.

Indications

Hyaluronic acid fillers offer multiple applications in both rejuvenation and facial harmonisation:

• Lip augmentation and definition
• Cheekbone projection and definition
• Correction of nasolabial folds and marionette lines
• Under-eye filler
• Chin and jawline definition
• Rhinomodelling
• Deep hydration (skinboosters)

The procedure

Needle or cannula infiltrations following a personalised plan. Duration: 20–40 minutes. Topical or local anaesthesia for comfort. Immediate visible results. The patient can resume their normal routine after the session.

Results

• Effect visible from the moment of application
• Progressive improvement in the following days
• Final result after product integration (7–10 days)
• Variable duration: 9 to 18 months, depending on the area and product type

Benefits

• Facial rejuvenation without surgery
• Immediate and natural results
• High personalisation capacity
• Improvement of skin hydration and quality
• Safe and biocompatible procedure
• No significant recovery time

Safety and contraindications

Excellent safety profile when performed by specialist physicians. Mild and temporary side effects: swelling, small bruises, sensitivity, mild transient asymmetries. Contraindicated during pregnancy, breastfeeding, active infections, autoimmune diseases, or hypersensitivity to components.